Title Page
Objective
General Introduction
Basic Anatomy of the Mammalian Genome
Inherited Phenotypes
Simple or Mendelian traits
These are inherited traits for which the observed phenotypic variation is entirely explained by (bi-)allelic segregation at a single locus and which segregate according to one of basic Mendelian inheritance patterns: autosomal recessive, dominant and codominant.
The relationship between genotype and phenotype is simple: all the observed phenotypic variation can be explained by the variation at a single locus.
Simple traits include autosomal, X-linked and Y-linked traits which can be recessive, dominant
Molecular basis of dominance / recessivity.
Genetic Linkage
Linkage Disequilibrium
Genetic Markers
Map Construction
QTL Mapping in Outbred Half-Sib Pedigrees
References